“…reproducibility problems attributed to antibodies can be blamed on “a two-headed monster” of poor antibodies and poor training.
Both are fuelled by lack of clear, commonly accepted guidelines about what is required to validate an antibody, and what information
companies should supply about the reagent’s performance.“
“However, to date, there is no universal standard. We therefore present our lab’s approach to the
“For the meantime, however, the responsibility ultimately lies with the researcher or laboratory director
to ensure that the antibodies used in their labs are validated for specificity and reproducibility.”
“Not only are antibody companies frequently bought and sold, they also change their business approach. Some companies transition from selling
licensed antibodies to producing their own antibodies. Companies also sell to one another to keep their catalogs thick and increase sales.”