γ-Catenin Antibody #2309

Catalog # Size Price Supplier
2309 100 µl $239.00 Cell Signaling Technology
Score
Citations
The number of citations demonstrates utilization by the research community.
0
Methods
Applications IF, IHC, IP, WB
Reactivity Ha, H, Mk, M, R

Specimen Types
Cell Lines C2C12, HEK293, HT-29, MCF-7
Overexpressed protein
Tissue Colon carcinoma, Lung carcinoma, Breast carcinoma
siRNA
Xenograft
  • Product Information
  • Citations
  • Protein Background
Concentration 10 western blots
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
UniProt P14923
Format Liquid

Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
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Applications
AP Affinity Purification
Array Array
ChIP Chromatin Immunoprecipitation
CyTOF Mass Cytometry
DB Dot Blot
EIA Enzyme Immunoassay
ELISA Enzyme Linked Immunosorbent Assay
ELISPOT Enzyme Linked Immunosorbent Spot
EM Electron Microscopy
EMSA Electrophoretic Mobility Shift Assay
FA Functional Assay
FC Flow Cytometry
HPLC High Performance Liquid Chromatography
ICC Immunocytochemistry
IF Immunofluorescence
IHC Immunohistochemistry
IP Immunoprecipitation
PLA Proximity Ligation Assay
RIA Radioimmunoassay
SDS-PAGE Sodium Dodecyl Sulfate Polyacrylamide gel electrophoresis
WB Western Blot
Species
All All Species Expected
B Bovine
Ca Canine
Ce C. elegans
Ck Chicken
Dr Drosophila
Fe Feline
Gp Guinea Pig
H Human
Ha Hamster
Hr Horse
M Mouse
Mi Mink
Mk Monkey
Ov Ovine
Pc Porcine
Pr Primate
R Rat
Rb Rabbit
Sh Sheep
X Xenopus
Yt Yeast
Zf Zebrafish